Red Devil or Red Devils may refer to:

• Doxorubicin, trade name Adriamycin, a chemotherapy drug nicknamed "red devil" for its deep red color and dangerous side effects
• Pyramid Head, a character in the Silent Hill 2 video game, nicknamed "red devil"
• Red Devil, Alaska, United States
• Red devil cichlid, two species of cichlid fish from genus Amphilophus
• Red Devil Energy Drink
• Red Devils (Parachute Regiment), nickname for the UK's Parachute Regiment and name of their parachute display team
• The Red Devils aerobatics team led by the late Charlie Hillard
• Red Devil, a DC comics superhero and former sidekick of the Blue Devil.

Music

• Red Devil (punk band), contemporary Philadelphia prog-punk band
• The Red Devils (band), 1920s Hawaiian band featuring King Ben Nawahi
• The Red Devils (blues band), 1980s-1990s Los Angeles-based blues band

Sports

• 1. FC Kaiserslautern, German football club
• Al-Ahly, Egyptian football club
• Belgium national football team
• Club Atlético Independiente, Argentine football club
• Club Toluca, Mexican football club
• Congo national football team
• Hapoel Tel Aviv F.C., Israeli football club
• Korea Republic national football team
• Manchester United F.C., English football club
• Red Devil Sport Club, a Russian based MMA training team/association
• Red Devil (supporters club), the official supporting group of the Korean Republic national football team
• Salford City Reds, English rugby league club

Schools

• Clarence High School (Clarence, New York)
• Dickinson College (Carlisle, Pennsylvania)
• Druid Hills High School (Atlanta, Georgia)
• Fyffe High School (Fyffe, Alabama)
• Green Bay East High School (Green Bay, Wisconsin)
• Grosse Ile High School (Grosse Ile, Michigan)
• Hinsdale Central High School (Hinsdale, Illinois)
• Hunterdon Central Regional High School (Flemington, New Jersey)
• Huntley Project High School (Worden, Montana)
• Lowell High School (Lowell, Indiana)
• Peekskill High School (Peekskill, New York)
• Pike High School (Indianapolis, Indiana)
• Plainedge, New York#Sports: Plainedge High School (Massapequa, New York)
• Richmond High School (Richmond, Indiana)
• San Francisco University High School (San Francisco, California)
• Springville High School (Springville, Utah)
• Murtaugh High School, Murtaugh Idaho

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