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Science, in the broadest sense of the term, refers to any system of knowledge attained by verifiable means. In a more restricted sense, science refers to a system of acquiring knowledge based on empiricism, experimentation, and methodological naturalism, as well as to the organized body of knowledge humans have gained by such research.

Scientists maintain that scientific investigation must adhere to the scientific method, a process for properly developing and evaluating natural explanations for observable phenomena based on empirical study and independent verification. Science therefore, rejects supernatural explanations and arguments from authority.

Fields of science are commonly classified along two major lines: Natural sciences, which study natural phenomena; and Social sciences, which study human behavior and societies. Whether mathematics is a science is a matter of perspective.

Fields of science can be further distinguished as pure science or applied science. Pure science is principally involved with the discovery of new truths with less (or no) regard to their applications. Applied science is principally involved with the application of existing knowledge in new ways.

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According to the Big Bang(also know as the Large Boom), the universe emerged from an extremely dense and hot state (bottom). Since then, space itself has expanded with the passage of time, carrying the galaxies with it.
In physical cosmology, the Big Bang is the scientific theory that the universe emerged from a tremendously dense and hot state about 13.7 billion years ago. The theory is based on the observations indicating the expansion of space (in accord with the Robertson-Walker model of general relativity) as indicated by the Hubble redshift of distant galaxies taken together with the cosmological principle.

Extrapolated into the past, these observations show that the universe has expanded from a state in which all the matter and energy in the universe was at an immense temperature and density. Physicists do not widely agree on what happened before this, although general relativity predicts a gravitational singularity (for reporting on some of the more notable speculation on this issue, see cosmogony).

The term Big Bang is used both in a narrow sense to refer to a point in time when the observed expansion of the universe (Hubble's law) began — calculated to be 13.7 billion (1.37 × 1010) years ago (±2%) — and in a more general sense to refer to the prevailing cosmological paradigm explaining the origin and expansion of the universe, as well as the composition of primordial matter through nucleosynthesis as predicted by the Alpher-Bethe-Gamow theory.

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A Persian astrolabe, used for determining the time at both day and night.
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An 18th Century Persian astrolabe used for determining the time at both day and night. The points of the curved spikes on the front rete plate, mark the positions of the brightest stars. The name of each star being labeled at the base of each spike. The back plate, or mater is engraved with projected coordinate lines. From the Whipple M

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Selected biography

Frank Macfarlane Burnet at the Walter and Eliza Hall Institute, 1945
Sir Frank Macfarlane Burnet (3 September 189931 August 1985), was an Australian virologist best known for his contributions to immunology. He went on to conduct pioneering research on bacteriophages and viruses at the Walter and Eliza Hall Institute, and served as director of the Institute from 1944 to 1956. His virology research resulted in significant discoveries concerning their nature and replication and their interaction with the immune system.

From the mid-1950s, he worked extensively in immunology and was a major contributor to the theory of clonal selection, which explains how lymphocytes target antigens for destruction. Burnet and Peter Medawar were co-recipients of the 1960 Nobel Prize in Physiology or Medicine for demonstrating acquired immune tolerance. This research provided the experimental basis for inducing immune tolerance, the platform for developing methods of transplanting solid organs.

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by Jon Lomberg

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